PUBLICATION

*, co-first authors; #, corresponding authors

Google Scholar Profile: Yuxuan Zheng

Selective Publications

A genome-wide CRISPR-based screen identifies KAT7 as a driver of cellular senescence
Science Translational Medicine
Wei Wang*, Yuxuan Zheng*, Shuhui Sun*, Wei Li*, Moshi Song, Qianzhao Ji, Zeming Wu, Zunpeng Liu, Yanling Fan, Feifei Liu, Jingyi Li, Concepcion Rodriguez Esteban, Si Wang, Qi Zhou, Juan Carlos Lzpisua Belmonte, Weiqi Zhang#, Jing Qu#, Fuchou Tang#, Guang-Hui Liu#
2021 13.575: eabd2655
  • F1000 Recommended
    • Link to publication
    Single-cell transcriptomic atlas of primate ovarian aging
    Cell
    Si Wang*, Yuxuan Zheng*, Jingyi Li*, Yang Yu*, Weiqi Zhang*, Moshi Song, Zunpeng Liu, Zheying Min, Huifang Hu, Ying Jing, Xiaojuan He, Liang Sun, Lifang Ma, Concepcion Rodriguez Esteban, Piu Chan, Jie Qiao, Qi Zhou, Juan Carlos Lzpisua Belmonte#, Jing Qu#, Fuchou Tang#, Guang-Hui Liu#
    2020 180.3: 585-600
  • Cover Story
  • F1000 Recommended
  • One of works awarded as "Top 10 Scientific Advances of 2020 in China (In-depth Analysis of Multi-organ Aging Biomarkers and Intervention Targets)" (see more)
  • One of works awarded as "Top 10 Progress in China’s Life Sciences in 2020 (Analysis the Regulation and Mechanism of Organ Aging)" (see more)
    • Link to publication
    Single-cell RNA-seq analysis reveals the progression of human osteoarthritis
    Annals of the Rheumatic Diseases
    Quanbo Ji*, Yuxuan Zheng*, Guoqiang Zhang, Yuqiong Hu, Xiaoying Fan, Yu Hou, Lu Wen, Li Li, Yameng Xu, Yan Wang#, Fuchou Tang#
    2019 78.1: 100-110
  • F1000 Recommended
  • Awarded as "China Orthopaedical Innovation Transformation Exhibition in 2019"
    • Link to publication
    Single-cell RNA-seq uncovers dynamic processes and critical regulators in mouse spermatogenesis
    Cell Research
    Yao Chen*, Yuxuan Zheng*, Yun Gao*, Zhen Lin*, Sunming Yang*, Tongtong Wang, Qiu Wang, Nannan Xie, Rong Hua, Mingxi Liu, Jiahao Sha, Michael D Griswold, Jinsong Li#, Fuchou Tang#, Ming-Han Tong#
    2018 28.9: 879-896
  • Cover Story
  • F1000 Recommended
  • Awarded as "Sanofi-Cell Research Outstanding Paper Award of 2018"
  • Awarded as "Outstanding Science and Technology Papers" (10 papes in the field of Life Sciences and Basic Medicine)
  • Selected as "30th Anniversary Collection: Top Articles from the Past 30 Years"
    • Link to publication

    2024

    Single-cell multi-omics analysis revealing immune features of inactivated COVID-19 vaccination in systemic lupus erythematosus patients
    Science Bulletin
    Yuxuan Zheng*, Siyuan Wang*, Xingyu Zhou*, Shitong Qiao*, Xin Zhao, Yuan Chen, Zijun Li, Zhanguo Li, Xiaolin Sun#, Shuguang Tan#, Jing He#, George Fu Gao#
    2024 (in press)
    Link to publication
    Mosaic RBD nanoparticle elicits immunodominant antibody responses across sarbecoviruses
    Cell Reports
    Chuanyu Liu*, Senyu Xu*, Yuxuan Zheng*, Yufeng Xie, Kun Xu, Yan Chai, Tingrong Luo, Lianpan Dai#, George Fu Gao#
    2024 43: 114235
    Link to publication
    Increased antibody titers but induced T-cell AICD and apoptosis response in COVID-19 convalescents by inactivated vaccine booster
    Microbiology Spectrum
    Jingmin Zhao*,#, Han Zhang*, Lina Jiang*, Fang Cheng*, Wei Li, Zihao Wang, Hongyang Liu, Shaohua Li, Yiyun Jiang, Meiling Li, Yan Li, Shuhong Liu, Min Fang, Xuyu Zhou, Xin Ye, Shousong Zhao#, Yuxuan Zheng#, Songdong Meng#
    2024 12.3: e0243523
    Link to publication

    2023 AND BEFORE

    Geneformer: a deep learning model for exploring gene networks (Research Comments)
    Science China Life Sciences
    Yuxuan Zheng*, George Fu Gao#
    2023 66.12: 2952-2954
    Link to publication
    Dosing interval regimen shapes potency and breadth of antibody repertoire after vaccination of SARS-CoV-2 RBD protein subunit vaccine
    Cell Discovery
    Shuxin Guo*, Yuxuan Zheng*, Zhengrong Gao*, Minrun Duan*, Sheng Liu, Pan Du, XiaoYu Xu, Kun Xu, Xin Zhao, Yan Chai, Peiyi Wang, Qi Zhao, George Fu Gao#, Lianpan Dai#
    2023 9.1: 79
    Link to publication
    Transcriptome landscape of African swine fever virus infection in swine macrophages at single-cell resolution
    Proceedings of the National Academy of the Sciences of the United States of America
    Yuxuan Zheng*, Su Li*, Shi-Hua Li*, Shaoxiong Yu*, Qihui Wang, Kehui Zhang, Liang Qu, Yuhai Bi#, Fuchou Tang#, Hua-Ji Qiu#, George Fu Gao#
    2022 119.19: e2201288119
    Link to publication
    Establishment of bovine expanded potential stem cells
    Proceedings of the National Academy of the Sciences of the United States of America
    Lixia Zhao*, Xuefei Gao*, Yuxuan Zheng*, Zixin Wang, Gaoping Zhao, Jie Ren, Jia Zhang, Jian Wu, Baojiang Wu, Yanglin Chen, Wei Sun, Yunxia Li, Jie Su, Yulin Ding, Yuan Gao, Moning Liu, Xiaochun Bai, Liangzhong Sun, Guifang Cao, Fuchou Tang, Siqin Bao, Pentao Liu#, Xihe Li#
    2021 118.15: e2018505118
    Link to publication
    A single-cell transcriptomic atlas of primate pancreatic islet aging
    National Science Review
    Jingyi Li*, Yuxuan Zheng*, Pengze Yan*, Moshi Song*, Si Wang*, Liang Sun, Zunpeng Liu, Shuai Ma, Juan Carlos Lzpisua Belmonte, Piu Chan, Qi Zhou, Weiqi Zhang#, Guang-Hui Liu#, Fuchou Tang#, Jing Qu#
    2021 8.2: nwaa127
  • One of works awarded as "Top 10 Scientific Advances of 2020 in China (In-depth Analysis of Multi-organ Aging Biomarkers and Intervention Targets)" (see more)
  • One of works awarded as "Top 10 Progress in China’s Life Sciences in 2020 (Analysis the Regulation and Mechanism of Organ Aging)" (see more)
    • Link to publication
    Deciphering primate retinal aging at single-cell resolution
    Protein & Cell
    Si Wang*, #, Yuxuan Zheng*, Qingqing Li*, Xiaojuan He, Ruotong Ren, Weiqi Zhang, Moshi Song, Huifang Hu, Feifei Liu, Guoqiang Sun, Shuhui Sun, Zunpeng Liu, Yang Yu, Piu Chan, Guo-Guang Zhao, Qi Zhou, Guang-Hui Liu#, Fuchou Tang#, Jing Qu#
    2021 12.11: 889-898
  • One of works awarded as "Top 10 Scientific Advances of 2020 in China (In-depth Analysis of Multi-organ Aging Biomarkers and Intervention Targets)" (see more)
  • One of works awarded as "Top 10 Progress in China’s Life Sciences in 2020 (Analysis the Regulation and Mechanism of Organ Aging)" (see more)
    • Link to publication
    Integrated transcriptomics and epigenomics reveal chamber-specific and species-specific characteristics of human and mouse hearts
    PLoS Biology
    Junpeng Gao*, Yuxuan Zheng*, Lin Li, Minjie Lu, Xiangjian Chen, Yu Wang, Yanna Li, Xiaomeng Liu, Yun Gao, Yunuo Mao, Peng Zhao, Jinan Zhang, Fuchou Tang, Lei Song#, Lu Wen#, Jizheng Wang#
    2021 19.5: e3001229
    Link to publication
    In vitro expansion of human sperm through nuclear transfer
    Cell Research
    Xiaoyu Merlin Zhang*, Keliang Wu*, Yuxuan Zheng*, Han Zhao*, Junpeng Gao, Zhenzhen Hou, Meiling Zhang, Jiaoyang Liao, Jingye Zhang, Yuan Gao, Yuanyuan Li, Lin Li, Fuchou Tang#, Zi-Jiang Chen#, Jinsong Li#
    2020 30.4: 356-359
    Link to publication
    Refined spatial temporal epigenomic profiling reveals intrinsic connection between PRDM9-mediated H3K4me3 and the fate of double-stranded breaks
    Cell Research
    Yao Chen*, Ruitu Lyu*, Bowen Rong*, Yuxuan Zheng*, Zhen Lin*, Ruofei Dai, Xi Zhang, Nannan Xie, Siqing Wang, Fuchou Tang#, Fei Lan#, Ming-Han Tong#
    2020 30.3: 256-268
    Link to publication
    Single-cell transcriptome analysis maps the developmental track of the human heart
    Cell Reports
    Yuli Cui*, Yuxuan Zheng*, Xixi Liu*, Liying Yan, Xiaoying Fan, Jun Yong, Yuqiong Hu, Ji Dong, Qingqing Li, Xinglong Wu, Shuai Gao, Jingyun Li, Lu wen, Jie Qiao#, Fuchou Tang#
    2019 26.7: 1934-1950
    Link to publication